BDBM50176259 (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol::CHEMBL201531::TRAMADOL

SMILES COc1cccc(c1)[C@@]1(O)CCCC[C@@H]1CN(C)C

InChI Key InChIKey=TVYLLZQTGLZFBW-ZBFHGGJFSA-N

Data  8 KI  17 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50176259   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.86E+3nMAssay Description:Inhibition of NET mediated norepinephrine uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50176259((1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphen...)
Affinity DataIC50:  790nMAssay Description:Inhibition of reuptake of NorepinephrineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank